CT Pulmonary Angiography (CTPA) is the standard imaging technique to evaluate pulmonary embolism (PE) and pulmonary vasculature. I’ll guide you step by step:
Patient Preparation
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Indications: Suspected pulmonary embolism, pulmonary artery abnormalities, vascular malformations, pre-surgical evaluation.
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Consent: Explain contrast use, possible side effects.
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Check labs: Serum creatinine / GFR (to assess kidney function).
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Check history: Allergy to iodine contrast, asthma, thyroid disease.
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IV Access: Large bore IV cannula (18–20G) in antecubital vein.
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Breath-hold training: Patient must hold breath during scan to avoid motion.
Scan Protocol
Scanner: Any multislice CT (64-slice or higher preferred).
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Patient position: Supine, head first.
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Scan range: From thoracic inlet to just below costophrenic angles.
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ECG gating: Not required (except for suspected RV strain/cardiac assessment).
Contrast Injection
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Contrast: Non-ionic iodinated contrast (e.g., 60–80 ml).
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Injection rate: 4–5 ml/sec (high flow).
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Use a power injector with saline chaser (30–40 ml).
Bolus Tracking (Smart Prep)
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ROI (Region of Interest): Main pulmonary artery / right ventricle outflow tract.
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Trigger threshold: ~100–150 HU.
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Start scan after 3–5 sec delay once threshold is reached.
Scan Parameters (Typical)
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kVp: 100–120 (depending on patient size).
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mAs: Automated (dose modulation ON).
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Slice thickness: 0.5–1.25 mm (thin slices for 3D).
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Pitch: 0.9–1.2.
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Rotation time: 0.5 sec.
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Reconstruction: Axial, coronal, sagittal, MIP (maximum intensity projection), VR (volume rendering).
Post-processing
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Review axial images first.
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Use MIP for vessel tracing.
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Evaluate pulmonary arteries from main PA → lobar → segmental → subsegmental levels.
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Check for: Filling defects, clot burden, right heart strain.
Tips for Best Quality
✅ Ensure tight bolus timing → scan during peak pulmonary artery opacification.
✅ Avoid respiratory motion → good breath-hold.
✅ Use saline flush → reduces streak artifacts from SVC/RA.
✅ In obese patients → increase kVp (120–140).
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